Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

作者:Wang Yunchen; Takki Sofia; Cheung Ocean; Xu Hongyi; Wan Wei; Ohrstrom Lars; Inge A Ken
来源:Chemical communications, 2017, 53(52): 7018-7021.
DOI:10.1039/c7cc03180g

摘要

Bismuth subgallate has been used in wound and gastrointestinal therapy for over a century. The combination of continuous rotation electron diffraction and sample cooling finally revealed its structure as a coordination polymer. The structure provides insight regarding its formula, poor solubility, acid resistance and previously unreported gas sorption properties.

  • 出版日期2017-7-4