Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides

作者:Jayawarna V; Ali M; Jowitt TA; Miller AE; Saiani A; Gough JE; Ulijn RV*
来源:Advanced Materials, 2006, 18(5): 611-+.
DOI:10.1002/adma.200501522

摘要

A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.

  • 出版日期2006-3-3