A simple method to fabricate electrochemical sensor systems with predictable high-redox cycling amplification

作者：Straver M G; Odijk M^*; Olthuis W; van den Berg A

来源：Lab on a Chip, 2012, 12(8): 1548-1553.

DOI：10.1039/c2lc21233a

In this paper an easy to fabricate SU8/glass-based microfluidic sensor is described with two closely spaced parallel electrodes for highly selective measurements using the redox cycling effect. By varying the length of the microfluidic entrance channel, a diffusion barrier is created for non-cycling species effectively increasing selectivity for redox cycling species. Using this sensor, a redox cycling amplification of similar to 6500x is measured using the ferrocyanide redox couple. Moreover, a simple, but accurate analytical expression is derived that predicts the amplification factor based on the sensor geometry.

• 出版日期2012