摘要

A clean and efficient synthesis of polysubstituted benzenes has been developed via sequential vinylogous Michael addition and nucleophilic cyclization reactions of arylethylidenemalonodinitriles with arylidenemalonodinitriles in the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]) employing L-proline as a catalyst.

  • 出版日期2012