Endoscopic resection combined with radiotherapy of posterior nasoseptal chondrosarcoma: a case report and literature review

作者：Hu, Bing; Liu, Wei; Zheng, Qingyin; Ren, Jihao^*

来源：International Journal of Clinical and Experimental Pathology, 2016, 9(5): 5760-5765.

• Chondrosarcoma
• nasal septum
• endoscope
• radiotherapy

Chondrosarcomas originating from the posteriornasal septum are rare. Surgical resection is the recommended treatment modality. Although remarkable advancements in endoscopic surgery and operation navigational system have allowed for the successful treatment of various sinonasal neoplasms, few sinonasal chondrosarcomas have been resected using an endoscopic approach sincethe first report of endoscopic excisiona decade ago. As well, seldom cases have been treated by a combination of endoscopic surgery with radiotherapy. Here we present a case of a posterior nasoseptal chondrosarcoma that extended to the bilateral ethmoid and sphenoid sinuses. Histopathological and immunohistochemical analysis confirmed grade II chondrosarcoma. After being treated by endoscopic surgery and radiotherapy, the patient showed no evidence of recurrence for five years. This present case highlights the endoscopic approach as a promising option for early stage chondrosarcomas which could lead to long-term cancer-free survival. In addition, the latest advances of radiotherapy are also reviewed.

• 出版日期2016
• 单位中南大学