New strategies in antitumor therapies based on apoptosis induction

作者：Martin Sabroso Cristina; Torres Suarez Ana Isabel

来源：Anales de la Real Academia Nacional de Farmacia, 2013, 79(2): 213-228.

• Apoptosis
• Anticancer agent
• Drug resistant

According to OMS, in 2030 will be a total of 11.5 million deaths by cancer. A high proportion of these tumors will be resistant to current anticancer agents, and therefore, in the last years an intense investigation has been done to search new targets for antitumor treatment. One of the most interesting targets is the apoptosis mechanism. Apoptosis is produced in physiological conditions as a growth tissue regulator mechanism, in equilibrium with cellular proliferation. Its deregulation could explain the pathogenesis of some malignant tumors.

• 出版日期2013