科研之友
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摘要
A concise and efficient approach for the construction of the tetracyclic carbon skeleton of retigeranic acid A is described. The key transformations include a novel Rh-catalyzed [3+2] cycloaddition of enyol to afford cyclopentanoid E, bearing two contiguous quaternary stereocenters at the bridgehead positions, and an intramolecular Pauson-Khand reaction to construct the advanced tetracyclic core structure of retigeranic acid A.
- 出版日期2015-9-1
- 单位中国海洋大学; 北京大学; 重庆大学; 北京大学深圳研究生院
