A New Method for the Facile Synthesis of Hydroxylated Flavones by Using Allyl Protection

作者:Nawghare B R; Sakate S S; Lokhande P D*
来源:Journal of Heterocyclic Chemistry, 2014, 51(2): 291-302.
DOI:10.1002/jhet.1580

摘要

The iodine-induced oxidative cyclization of 2-hydroxychalcones provides a simple, highly efficient approach to various hydroxy flavones and analogues. This process is run under mild conditions, tolerates various functional groups, and provides hydroxy flavones in good to excellent yield. The allyl-protected acetophenones and benzaldehydes were smoothly deallylated under similar conditions.

  • 出版日期2014-3