An efficient and catalyst-free synthesis of N-arylidene-2-arylimidazo[1,2-a]pyridine-3-ylamine derivatives via Strecker reaction under controlled microwave heating

作者：Hameed Afaf Mohamed Abdel^*; Moustafa Moustafa Sherief; Al Mousawi Saleh Mohammed; Awed Reham R; Sadek Kamal Usef

来源：Green Processing and Synthesis, 2017, 6(4): 371-375.

DOI：10.1515/gps-2017-0019

• catalyst free
• microwave heating
• multicomponent reaction
• N-aryldene-2-arylimidazo[1,2-a]-pyridine-3-ylamine
• Strecker reaction

An efficient one-pot multicomponent reaction of 2-aminopyridine with aromatic aldehydes and either benzoyl cyanide or cyanamide in pyridine under controlled microwave heating afforded N-aryldene-2-arylimidazo[1,2-a]-pyridine-3-ylamine derivatives. The reaction is catalyst free and is of high atom economy.

• 出版日期2017-8