A Selective O- and N-Acylation Protocol for Carbamyl Chloride

作者:Lang Ming*; Yan Ruizuo; Wang Yuqiang; Yu Pei
来源:Chinese Journal of Organic Chemistry, 2014, 34(6): 1227-1230.
DOI:10.6023/cjoc201311035

摘要

A practical and efficient selective O- and N-acylation protocol for carbamyl chloride by using different bases was developed. The structures of the products were identified by H-1 NMR, H-13 NMR, ESI-MS and HRMS. The mechanism for the selective acylation is proposed.

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