Generating iPSCs: Translating Cell Reprogramming Science into Scalable and Robust Biomanufacturing Strategies

作者：Silva Marli; Daheron Laurence; Hurley Hannah; Bure Kim; Barker Richard; Carr Andrew J; Williams David; Kim Hae Won; French Anna; Coffey Pete J; Cooper White Justin J; Reeve Brock; Rao Mahendra; Snyder Evan Y; Ng Kelvin S; Mead Benjamin E; Smith James A; Karp Jeffrey M; Brindley David A; Wall Ivan^*

来源：Cell Stem Cell, 2015, 16(1): 13-17.

DOI：10.1016/j.stem.2014.12.013

Induced pluripotent stem cells (iPSCs) have the potential to transform drug discovery and healthcare in the 21st century. However, successful commercialization will require standardized manufacturing platforms. Here we highlight the need to define standardized practices for iPSC generation and processing and discuss current challenges to the robust manufacture of iPSC products.

• 出版日期2015-1-8