Analysis of Two Cephalosporin Drugs Ceftriaxone and Cefepime Alone and in Presence of Two beta-Lactamase Inhibitors Sulbactam and Tazobactam

作者：Shrestha Bhupendra^*; Bhuyan Nihar Ranjan; Sinha Barij Nayan

来源：Asian Journal of Chemistry, 2011, 23(11): 4751-4756.

• Ceftriaxone
• Cefepime
• Sulbactam
• Tazobactam
• beta-lactamase inhibitors

The beta-lactam is the most widely prescribed antibiotic of the all antibiotics. The most important problem related with this type of antibiotic is their susceptibility to beta-lactamases which renders them ineffective. Therefore, use of inhibitors of beta-lactamases that are structurally similar to beta-lactam antibiotics are very much essential. In this review, the authors have extensively presented the analytical methods available for two widely used cephalosporin drugs ceftriaxone and cefepime along with two beta-lactamases inhibitors sulbactam and tazobactam.

• 出版日期2011-11