Resistive vibration exercise reduces lower limb muscle atrophy during 56-day bed-rest

作者：Belavy D L^*; Miokovic T; Armbrecht G; Rittweger J; Felsenberg D

来源：The Journal of Musculoskeletal and Neuronal Interactions, 2009, 9(4): 225-235.

DOI：10.1016/j.bone.2009.01.191

• Spaceflight
• Berlin Bed Rest Study
• Magnetic Resonance Imaging
• Microgravity
• Countermeasures

Objectives: The current study aimed to examine the effectiveness of a resistive vibration exercise countermeasure during prolonged bed-rest in preventing lower-limb muscle atrophy. Methods: 20 male subjects underwent 56-days of bed-rest and were assigned to either an inactive control, or a countermeasure group which performed high-load resistive exercises ( including squats, heel raises and toe raises) with whole-body vibration. Magnetic resonance imaging of the lower-limbs was performed at two-weekly intervals. Volume of individual muscles was calculated. Results: Countermeasure exercise reduced atrophy in the triceps surae and the vastii muscles (F>3.0, p<.025). Atrophy of the peroneals, tibialis posterior and toe flexors was less in the counter-measure-subjects, though statistical evidence for this was weak (F <= 2.3, p >=.071). Atrophy in the hamstring muscles was similar in both groups (F<1.1, p>.38). The adductor longus, sartiorius and rectus femoris muscles showed little loss of muscle volume during bed-rest (F<1.7, p>.15). Conclusions: The countermeasure exercise programme was effective in reducing atrophy in the extensors of the knee and ankle but not the hamstrings.

• 出版日期2009-12