Arterial, Venous, and Cerebrospinal Fluid Flow: Simultaneous Assessment with Bayesian Multipoint Velocity-encoded MR Imaging

作者：Knobloch Verena; Binter Christian; Kurtcuoglu Vartan; Kozerke Sebastian^*

来源：Radiology, 2014, 270(2): 566-573.

DOI：10.1148/radiol.13130840

Purpose: To measure arterial, venous, and cerebrospinal fluid (CSF) velocities simultaneously by using Bayesian multi-point velocity-encoded magnetic resonance (MR) imaging and to compare interacquisition reproducibility relative to that of standard phase-contrast MR imaging for sequential measurements of arterial, venous, and CSF velocities.
Materials and Methods: This study was approved by the local ethics committee, and informed consent was obtained from all subjects. Simultaneous measurement of blood and CSF flow was performed at the C1-C2 level in 10 healthy subjects (mean age, 24.4 years +/- 2.7; five men, five women) by using accelerated Bayesian multi-point velocity-encoded MR imaging. Data were compared with those obtained from two separate conventional phase-contrast MR imaging acquisitions, one optimized for arterial and venous blood flow (velocity encoding range, +/- 50 cm/sec) and the other optimized for CSF flow (velocity encoding range, +/- 10 cm/sec), with an imaging time of approximately 2 minutes each. Data acquisition was repeated six times. Intraclass correlation coefficient (ICC) and linear regression were used to quantify interacquisition reproducibility.
Results: There was no significant difference in arterial blood flow measured with Bayesian multipoint velocity-encoded MR imaging and that measured with phase-contrast MR imaging (mean ICC, 0.96 +/- 0.03 vs 0.97 +/- 0.02, respectively). Likewise, there was no significant difference between CSF flow measured with Bayesian multipoint velocity-encoded MR imaging and that measured with phase-contrast MR imaging (mean ICC, 0.97 +/- 0.02 vs 0.96 +/- 0.05, respectively). For venous blood flow, the ICC with Bayesian multipoint MR imaging was significantly larger than that with conventional phase-contrast MR imaging (mean, 0.75 +/- 0.23 vs 0.65 +/- 0.26, respectively; P = .016).
Conclusion: Bayesian multipoint velocity-encoded MR imaging allows for simultaneous assessment of fast and slow flows in arterial, venous, and CSF lumina in a single acquisition. It eliminates the need for vessel-dependent adjustment of the velocity-encoding range, as required for conventional sequential phase-contrast MR imaging measurements.

• 出版日期2014-2