New modular P-chiral ligands for Rh-catalyzed asymmetric hydrogenation

作者：Bondarev Oleg G^*; Goddard Richard

来源：Tetrahedron Letters, 2006, 47(51): 9013-9015.

DOI：10.1016/j.tetlet.2006.10.122

• asymmetric reactions
• phosphorus ligands
• rhodium
• hydrogenation

New modular P-chiral ligands have been prepared from commercially available (S)-alpha,alpha-diphenylprolinol. With these new types of ligands, up to 95% ee was achieved in the Rh-catalyzed asymmetric hydrogenation of functionalized olefins.

• 出版日期2006-12-18