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摘要
Diastereomerically pure tridentate heteroorganic ligands containing hydroxyl, sulfinyl, and amino moieties as nucleophilic centers, capable of binding various organometallic reagents, have proven to be highly efficient catalysts in enantioselective aza-Henry reactions to give the desired products in very high yields (up to 98%) and with ees of up to 95%. The influence of the stereogenic centers, located on the sulfinyl sulfur atom and in the amino moiety on the stereochemical course of the reaction is also discussed.
- 出版日期2011-5-31
