Atg7 in AML: a double-edged sword?

作者:Grant Steven*
来源:Blood, 2016, 128(9): 1163-1165.
DOI:10.1182/blood-2016-07-722652

摘要

In this issue of Blood, Piya et al have identified the autophagy-related E1 ligase Atg7, a critical autophagy component associated with unfavorable outcomes in acute myeloid leukemia (AML), as a potential target in this disease.(1) If validated, this study could provide a foundation for disrupting Atg7 in AML therapy.

  • 出版日期2016-9-1