Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

作者:Pascual Lluis; El Sayed Sameh; Martinez Manez Ramon*; Costero Ana M; Gil Salvador; Gavina Pablo; Sancenon Felix*
来源:Organic Letters, 2016, 18(21): 5548-5551.
DOI:10.1021/acs.orglett.6b02793

摘要

Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).

  • 出版日期2016-11-4