A Method that Will Captivate U

作者:Martin Sophie; Coller Jeff
来源:Molecular Cell, 2015, 59(5): 716-717.
DOI:10.1016/j.molcel.2015.08.017

摘要

In an age of next-generation sequencing, the ability to purify RNA transcripts has become a critical issue. In this issue, Duffy et al. (2015) improve on a pre-existing technique of RNA labeling and purification by 4-thiouridine tagging. By increasing the efficiency of RNA capture, this method will enhance the ability to study RNA dynamics, especially for transcripts normally inefficiently captured by previous methods.

  • 出版日期2015-9-3