sp(3) C-H activation via exo-type directing groups

作者:Xu Yan; Dong Guangbin*
来源:Chemical Science, 2018, 9(6): 1424-1432.
DOI:10.1039/c7sc04768a

摘要

The application of exo-type directing groups (DGs) has led to the discovery of a wide range of novel C(sp(3))-Hactivation methods, which allow efficient and site-selective functionalization of alcohol and amide derivatives. In this mini-review we discuss the challenges of this field and summarize the achievements, including DG designs, reaction discoveries and mechanistic studies.

  • 出版日期2018-2-14