Modification of P(MMA-GMA-DVB) Microspheres by Polyasparagine Derivatives

作者：Liu Hongbo^*; Yang Hui; Tang Yunzi; Shen Yang; Xu Qian

来源：Acta Chimica Sinica, 2010, 68(20): 2125-2129.

• soap-free emulsion polymerization
• polysuccinimide
• fluorescent microsphere

Narrow-dispersed P(MMA-GMA-DVB) (PMGD) microspheres with different amout of DVB from 20 to 50 weight percentages were prepared by soap-free emulsion polymerization and polysuccinimide (PSI) was prepared by polycondensation of L-aspartic acid (L-ASP) using phosphoric acid as a catalyst in sulfolane/mesitylene solvent Then, PSI was attached to the surface of PMGD microspheres containing different amount of DVB in N,N-dimethylformamide solvent The elemental analysis results showed that the largest amount of PSI was attached to the surface of P(MMA-GMA-DVB) microspheres when the weight content of DVB was 40% Then the remains of active rings of the PSI on the surface of microspheres were opened by ethanediamine, at last, fluorescent microspheres were achieved by reacting with fluorescein isothiocyanate (FITC)

• 出版日期2010-10-28
• 单位上海工程技术大学