Acute myelitis as presenting symptom of HIV-HTLV-1 co-infection

作者：Cucca A^*; Stragapede L; Antonutti L; Catalan M; Caracciolo I; Valentinotti Romina; Granato A; D'Agaro P; Manganotti P

来源：Journal of NeuroVirology, 2016, 22(6): 861-865.

DOI：10.1007/s13365-016-0455-2

• Myelitis
• HIV
• HTLV

A 21-year-old woman presented with acute-onset spastic paraparesis. The MRI spinal scan revealed a contrast-enhanced T2 hyperintensity between C5-T2. The most common neurotropic pathogens were excluded by first level tests. Under suspicion of an acute immune-mediated myelitis, a corticosteroid therapy was administered. However, a seropositivity for both human immunodeficiency virus (HIV) type 1 and human T-lymphotropic virus (HTLV) subsequently emerged. An antiretroviral therapy was started while steroids discontinued. Patient's clinical conditions remained unchanged. HIV-HTLV-1 co-infection should be included in the differential diagnosis of any acute myelitis, even in patients with a preserved immune status and no risk factors.

• 出版日期2016-12