Application value of shear wave elastography technique in diagnosis of chronic allograft nephropathy

作者：Yang, Jin-Ru^*; Wang, Fei-Qian; Li, Ning; Pan, Wen-Qian; Ai, Hong

来源：International Journal of Clinical and Experimental Medicine, 2016, 9(6): 9449-9454.

• Ultrasonography
• renal transplantation
• shear wave elastography technique

Objective: To investigate the application of shear wave elastography (SWE) in chronic allograft nephropathy. Methods: 82 patients with renal transplantation were all treated with conventional ultrasound and shear wave elastography. Group status: normal renal function group after treating with renal transplantation (Scr <134 mol/L, 36 patients), chronic allograft nephropathy (CAN) group after renal transplantation over 6 months (Scr >134 mol/L, 46 patients). Results: 1. The SWE values of renal cortex in CAN group were higher than those in normal renal function group, P < 0.05. 2. There was a positive correlation between SWE values and Scr, and meanwhile, the difference between them was statistically significant, P < 0.05. 3. The ROC curves of each SWE value showed that the sensitivity and specificity of Mean were as high as 92.9%. Conclusion: Shear wave elastography is helpful for the judgment of the hardness of chronic allograft nephropathy, which is expected to provide a new, noninvasive and convenient method for the monitoring of renal function and renal hardness after renal transplantation.

• 出版日期2016
• 单位西安交通大学