An efficient and simple method for synthesis of 2,2-disubstituted-2H-chromenes by condensation of a phenol with a 1,1-disubstituted propargyl alcohol using BF3 center dot Et2O as the catalyst

作者：Madabhushi Sridhar^*; Jillella Raveendra; Godala Kondal Reddy; Mallu Kishore Kumar Reddy; Beeram China Ramanaiah; Chinthala Narsaiah

来源：Tetrahedron Letters, 2012, 53(39): 5275-5279.

DOI：10.1016/j.tetlet.2012.07.077

• 2,2-Disubstituted-2H-chromenes
• Phenol
• Cyclocondensation
• 1,1-Disubstituted propargyl alcohol
• BF3 center dot Et2O
• Lewis acid catalysis

An efficient and simple method for the synthesis of 2,2-disubstituted-2H-chromenes by one-step cyclocondensation of a phenol with a variety of 1,1-disubstituted propargyl alcohols using BF3 center dot Et2O as the catalyst is described.

• 出版日期2012-9-26