An Efficient Copper-Catalyzed Carbon-Sulfur Bond Formation Protocol in Water

作者：Ke, Fang; Qu, Yanyang; Jiang, Zhaoqiong; Li, Zhengkai; Wu, Di; Zhou, Xiangge^*

来源：Organic Letters, 2011, 13(3): 454-457.

DOI：10.1021/ol102784c

• CROSS-COUPLING REACTIONS
• ARYL HALIDES
• C-S
• NUCLEOPHILIC-SUBSTITUTION
• NICKEL-CATALYST
• N-ARYLATION
• THIOLS
• PALLADIUM
• ARYLTHIOLATION
• SYSTEM

An efficient protocol of copper-catalyzed C-S bond formation between aryl halides and potassium thiocyanate leading to diaryl sulfides is reported. A variety of diaryl sulfides can be synthesized In good to excellent yields up to 94%.

• 出版日期2011-2-4
• 单位四川大学