A New Ring Expansion for a Chiral Hexahydroazulene Skeleton Possessing an Angular Methyl Group

作者：Adachi Masaatsu^*; Komada Takema; Nishikawa Toshio

来源：Journal of Organic Chemistry, 2011, 76(16): 6942-6945.

DOI：10.1021/jo201153h

A new synthetic route for a pseudoguaiane ring system is described. The synthesis features an Ireland-Claisen rearrangement for constructing the trans-fused ring system, followed by a new ring expansion to yield a bicyclo[5.3.0]decane ring system possessing an angular methyl group.

• 出版日期2011-8-19