Diet and Exercise Improve Neutrophil to Lymphocyte Ratio in Overweight Adolescents

作者:Wang, R.; Chen, P. J.*; Chen, W. H.
来源:International Journal of Sports Medicine, 2011, 32(12): 982-986.
DOI:10.1055/s-0031-1283185

摘要

Neutrophil to lymphocyte ratio and levels of pro-inflammatory cytokines were evaluated in overweight, male Chinese adolescents upon completing a 4-week diet and physical exercise intervention. 43 recruited, non-randomized adolescents (body mass index >25kg/m(2)) completed the controlled study. Anthropometric and biologic parameters were measured pre- and post-intervention. After the 4-week intervention, participants exhibited a significant decrease in body mass, body mass index, percentage body fat, basal heart rate, diastolic blood pressure, and all body shape indices tested. A significant decrease in serum lipids (except high-density lipoprotein cholesterol) and insulin levels was observed post-intervention. The neutrophil to lymphocyte ratio was significantly lower post-intervention. Bivariate correlation analyses showed that decrement in Delta neutrophil to lymphocyte ratio significantly correlated with decrement in Delta interleukin-6 and Delta white blood cell count. Thus, a 4-week diet and physical exercise intervention significantly reduces the neutrophil to lymphocyte ratio in a population of overweight, male adolescents. Weight loss caused by the intervention was associated with a significant decrease of pro-inflammatory cytokine levels.

  • 出版日期2011-12
  • 单位上海体育学院

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