An efficient one-pot synthesis of C-2-symmetric triazolophanes by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction

作者：Rajesh R; Periyasami G; Raghunathan R^*

来源：Tetrahedron Letters, 2010, 51(14): 1896-1898.

DOI：10.1016/j.tetlet.2010.02.020

• 1,3-Dipolar cycloaddition
• Triazole
• Click chemistry
• Triazolophanes
• CuAAC

A facile and efficient one-pot synthesis of 12-15-membered triazolophanes has been accomplished using CuAAC methodology. The formation of triazolophanes was confirmed by spectral analysis and the products were isolated in good yield. The effect of solvents on this reaction was also studied.

• 出版日期2010-4-7