Magnetic resonance fingerprinting

作者：Ma, Dan; Gulani, Vikas; Seiberlich, Nicole; Liu, Kecheng; Sunshine, Jeffrey L.; Duerk, Jeffrey L.; Griswold, Mark A.^*

来源：Nature, 2013, 495(7440): 187-192.

DOI：10.1038/nature11971

• STATE FREE PRECESSION
• SIGNAL RECOVERY
• SPIRAL TRAJECTORIES
• SENSING MRI
• TIME
• T-2
• BRAIN
• QUANTIFICATION
• TRUEFISP
• T2

Magnetic resonance is an exceptionally, powerful and versatile measurement technique. The basic structure of a magnetic resonance experiment has remained largely unchanged for almost 50 years, being mainly restricted to the qualitative probing of only a limited set of the properties that can in principle be accessed by this technique. Here we introduce an approach to data acquisition, post-processing and visualization which we term 'magnetic resonance fingerprinting' (MRF) - that permits the simultaneous non-invasive quantification of multiple important properties of a material or tissue. MRF thus provides an alternative way to quantitatively detect and analyse complex changes that can represent physical alterations of a substance or early indicators of disease. MRF can also be used to identify the presence of a specific target material or tissue, which will increase the sensitivity, specificity and speed of a magnetic resonance study, and potentially lead to new diagnostic testing methodologies. When-paired with an appropriate pattern-recognition algorithm, MRF inherently suppresses measurement errors and can thus improve measurement accuracy.

• 出版日期2013-3-14