Microwave Synthesis, Spectral, Thermal and Antimicrobial Activities of Some Transition Metal Complexes Involving 2-Amino-6-nitrobenzothiazole Moiety

作者：Mishra A P; Jain Rajendra K^*

来源：Proceedings of the National Academy of Sciences India Section A-Physical Sciences, 2013, 83(3): 213-223.

DOI：10.1007/s40010-013-0082-8

• Microwave synthesis
• 2-Amino-6-nitrobenzothiazole
• Thermal analysis
• Biological activity

The coordination complexes of Cr(III), Co(II), Ni(II) and Cu(II) derived from 5-bromosalicylidene-2-amino-6-nitrobenzothiazole and 2-hydroxy-3-methoxybenzylidene-2-amino-6-nitrobenzothiazole have been synthesized by conventional as well as microwave methods. These compounds have been characterized by elemental analysis, FT-IR, molar conductance, electronic spectra, H-1-NMR, ESR, magnetic susceptibility, and thermal analysis. The complexes are coloured and stable in air. Analytical data revealed that all the complexes exhibited 1:2 (metal:ligand) ratio with coordination number 4 or 6. IR data shows that the ligand coordinates with the metal ions in a bidentate manner through the phenolic oxygen and azomethine nitrogen. Thermal data show degradation pattern of the complexes. The thermal behavior of metal complexes shows that the hydrated complexes loses water molecules of hydration in the first step; followed by decomposition of ligand molecules in the subsequent steps. The Schiff base and metal complexes show a good activity against the Gram-positive bacteria; Staphylococcus aureus and Gram-negative bacteria; Escherichia coli and fungi Aspergillus niger and Candida albicans. The antimicrobial results also indicate that the metal complexes are better antimicrobial agents as compared to the Schiff bases.

• 出版日期2013-9