Anodal tDCS during face-name associations memory training in Alzheimer%26apos;s patients

作者：Cotelli Maria^*; Manenti Rosa; Brambilla Michela; Petesi Michela; Rosini Sandra; Ferrari Clarissa; Zanetti Orazio; Miniussi Carlo

来源：Frontiers in Aging Neuroscience, 2014, 6: 38.

DOI：10.3389/fnagi.2014.00038

• memory
• stimulation
• dementia
• training
• tDCS

Objective: Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer%26apos;s disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. %26lt;br%26gt;Methods: Thirty six AD patients were randomly assigned to one of three study groups: Group 1, AtDCS plus individualized computerized memory training; Group 2, placebo tDCS plus individualized computerized memory training; Group 3, AtDCS plus motor training. %26lt;br%26gt;Results: A general improvement in performance was observed after 2 weeks of memory training. Both the anodal tDCS plus individualized computerized memory training and the placebo tDCS plus individualized computerized memory training groups had significantly improved performances at 2 weeks compared with the AtDCS plus motor training group. %26lt;br%26gt;Conclusion: Our findings suggest a beneficial effect of individualized memory rehabilitation in AD patients.

• 出版日期2014-3-19