An unusual sarcomatous retroperitoneal metastasis. A rare case report with a brief literature review

作者：Lazar A M^*; Straja N D; Bratucu E

来源：Chirurgia, 2012, 107(1): 108-114.

• retroperitoneal metastasis
• retroperitoneal sarcoma
• chondrosarcoma
• extremity chondrosarcoma
• alkaline phosphatase

Retroperitoneal sarcomas are rare tumors associated with a high rate of recurrence and very bad prognosis. Their only efficient treatment is a negative-margin surgical resection that is extremely difficult to achieve. Retroperitoneal metastases from extremity sarcomas are considered unusual. In literature, such a metastatic pattern is described extremely rarely. In this paper we report a case of a very aggressive extremity chondrosarcoma, associated with local recurrence, multiple distant metastases, that finally led to a retroperitoneal metastasis. The recurrence and progression of the sarcoma in this localization were impressive, with a fast overcome of therapeutic options. Chemo-and radiotherapy have not proved to be efficacious in this context and they could have had a role in the deterioration of patient state of health. New tumor markers for the detection and follow-up of these tumors should be considered.

• 出版日期2012-2