Analysis of Brain Evoked Potentials Based on Digital Registered Single-Trial Responses

作者：Kipinski Lech; Maciejowski Andrzej^*

来源：Advances in Clinical and Experimental Medicine, 2010, 19(3): 289-299.

• single-trial EPs
• averaging
• variability of brain evoked responses
• ongoing EEG-noise
• maximum likelihood method
• EPs mapping
• time-frequency analysis

Studies of brain evoked responses variability (e. g. habituation effect, relationships between spontaneous brain activity and evoked potentials (EPs) or ongoing EEG-noise analysis) need non-averaged, single-trial signals, which were rarely registered in Poland. The Department of Pathophysiology of Wroclaw Medical University was for many years gathering a lot of digital, binary data acquired by STELLA and NEUROMIC own-constructed measurement systems. This data are very interesting for planned research. In this paper the authors present a review of brain evoked responses variability and describe modern methods of analysis of non-averaged, single-trial responses. In order to achieve this, the authors want to take advantage of progressive mathematical tools, e.g. time-frequency analysis methods and advanced statistical techniques as well as high-tech IT tools. Selected methods are illustrated with the use of own measurement material. They will be used in research of the function of human nervous system based on recorded single-trial responses. In the future, it will be used in verification of their clinical applications (Adv Clin Exp Med 2010, 19, 3, 289-299).

• 出版日期2010