Neuroimaging experience in pediatric Horner syndrome

作者：Kadom Nadja^*; Rosman N Paul; Jubouri Shams; Trofimova Anna; Egloff Alexia M; Zein Wadih M

来源：Pediatric Radiology, 2015, 45(10): 1535-1543.

DOI：10.1007/s00247-015-3341-9

• Children
• Computed tomography
• Horner syndrome
• Magnetic resonance imaging
• Oculosympathetic pathway

Horner syndrome in children is rare. The frequency and spectrum of malignancy as the cause of Horner syndrome in children remains unclear. Also unclear is whether the imaging work-up should include the entire oculo-sympathetic pathway or should be more targeted. In addition, the value of cross-sectional angiographic imaging in Horner syndrome is uncertain.
To review imaging pathology in a cohort of children with Horner syndrome at a major academic pediatric medical center.
We reviewed a 22-year period of CT and MR imaging studies in children with a clinical diagnosis of Horner syndrome referred for imaging.
We found 38 patients who fulfilled study criteria of Horner syndrome and 6/38 had relevant imaging findings: 2/6 etiologies were neoplastic (congenital neuroblastoma and central astrocytoma), 1/6 had a vascular abnormality (hypoplastic carotid artery), 1/6 had maldevelopment (Chiari I malformation), and 2/6 had inflammatory/traumatic etiology (viral cervical lymphadenopathy, post jugular vein cannulation). There was a similar number of congenital and acquired pathologies. The malignancies were found at any level of the oculosympathetic pathway.
There are treatable causes, including malignancies, in children presenting with Horner syndrome, which justify imaging work-up of the entire oculosympathetic pathway, unless the lesion level can be determined clinically.

• 出版日期2015-9