Left Atrial Appendage Closure

作者：Lin Albert C^*; Knight Bradley P

来源：Progress in Cardiovascular Diseases, 2015, 58(2): 195-201.

DOI：10.1016/j.pcad.2015.07.009

• Atrial fibrillation
• Left atrial appendage
• Left atrial appendage closure

Stroke or systemic embolism is a devastating consequence of atrial fibrillation (AF) due to thrombus formation in the left atrial appendage (LAA). AF causes thrombus formation in the LAA due to both the loss of atrial systole and the unique anatomic features of the LAA. Oral anticoagulation is a well established and effective therapy to reduce the risk of stroke in AF patients, albeit with a risk of bleeding. LAA closure is a possible alternative to oral anticoagulation in the prevention of stroke or systemic embolism in AF.

• 出版日期2015-10
• 单位西北大学