Disclosing the nature of thermo-responsiveness of poly(N-isopropyl acrylamide)-based polymeric micelles: aggregation or fusion?

作者：Wang, Fangyingkai; Du, Jianzhong^*

来源：Chemical communications, 2015, 51(56): 11198-11201.

DOI：10.1039/c5cc02641e

• CROSS-LINKED MICELLES
• CONTROLLED-RELEASE
• HOMOPOLYMER VESICLES
• COPOLYMER MICELLES
• DIBLOCK COPOLYMER
• BLOCK-COPOLYMER
• CHAINS
• NANOPARTICLES
• MORPHOLOGY
• MEMBRANE

The apparent size increase of poly(N-isopropyl acrylamide) ( PNIPAM)-based polymericmicelles upon heating was usually ascribed to their volume growth or aggregation in aqueous solution. Herein we designed a photo-cross-linkable PNIPAM-based copolymer and proposed another thermo-responsive behaviour - fusion, which is disclosed by transmission electron microscopy (TEM) after in situ fixing morphologies at desired temperatures.

• 出版日期2015
• 单位同济大学