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摘要
To evaluate whether tumour stiffness on sonoelastography is associated with axillary nodal metastasis in T1 breast carcinoma patients. Between May 2006 and December 2010, 200 consecutive women (mean age, 51.6; range, 27 - 81 years) who underwent B-mode ultrasound (US), sonoelastography, and curative surgery with axillary nodal evaluation for clinically node negative T1 breast carcinomas (mean invasive tumour size, 12.4; range, 3 - 20 mm at pathology) were identified. The association between the elasticity score of the tumour and histopathological axillary nodal status was evaluated using a logistic regression model after controlling for imaging and clinicopathological variables of the tumour. The overall incidence of axillary nodal metastasis was 15.5 % (31 of 200). Axillary nodal metastasis was significantly more frequent in tumours with elasticity scores a parts per thousand yen4 than in tumours with elasticity scores < 4 (21.7 % vs. 4.2 %; P < 0.001). At multivariate analysis, an elasticity score a parts per thousand yen4 [odds ratio (OR), 6.95; P = 0.004], US size > 10 mm (OR, 5.98; P = 0.022), and lymphovascular invasion (OR, 10.68; P < 0.001) of tumours were independently associated with axillary nodal metastasis. Tumour stiffness on sonoelastography is independently associated with axillary nodal metastasis in T1 breast carcinoma patients. aEuro cent Prediction of axillary nodal status using imaging techniques is valuable. aEuro cent High ultrasound elasticity scores of T1 tumours were associated with axillary metastasis aEuro cent Node-positive T1 tumours frequently had elasticity scores 4 or 5. aEuro cent Sonoelastography might render axillary surgery unnecessary in T1 breast carcinoma patients.
- 出版日期2013-11
