A New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department: Mean Platelet Volume

作者：Talay Fahrettin^*; Ocak Tarik; Alcelik Aytekin; Erkuran Kursat; Akkaya Akcan; Duran Arif; Demirhan Abdullah; Kurt Ozlem Kar; Asuk Zehra

来源：African Health Sciences, 2014, 14(1): 94-99.

DOI：10.4314/ahs.v14i1.15

• Acute pulmonary embolism
• emergency department
• mean platelet volume
• thrombus

Objective: To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).
Methods: Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.
Results: A total of 315 consecutive patients were analyzed, including 150 patients (53.44 +/- 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 +/- 13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42 +/- 1.22 fl vs. 8.04 +/- 0.89 fl, p < 0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).
Conclusions: MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.

• 出版日期2014