High Levels of Serum Uric Acid Impair Development of Coronary Collaterals in Patients With Acute Coronary Syndrome

作者：Duran Mustafa^*; Ornek Ender; Murat Sani N; Turfan Murat; Vatankulu Mehmet A; Ocak Ayse; Doger Cihan; Yalcin Ahmet A; Demircelik Muhammed B

来源：Angiology, 2012, 63(6): 472-475.

DOI：10.1177/0003319711422433

• serum uric acid
• coronary collateral vessels
• acute coronary syndrome

We evaluated the association of serum uric acid (SUA) level and development of coronary collateral vessels (CCVs) in patients with acute coronary syndrome (ACS). Patients (n = 224) with ACS were included in the study. Coronary collateral vessels were graded according to the Rentrop scoring system. Rentrop grade 0 was accepted as absence of CCV (group >= 1; n = 117) and Rentrop grade ayen1 was accepted as presence of CCV (group 2; n = 107). Rentrop 0-1 (poor CCV) were determined in 167 patients and Rentrop 2-3 (good CCV) were determined in 57 patients. Both presence of CCV (P < .001) and development of good CCV (P = .003) were significantly associated with low levels of SUA. We suggest that high levels of SUA affect the CCV development negatively in nondiabetic and nonhypertensive patients with ACS.

• 出版日期2012-8