Alkaloids from the Tribe Bocconieae (Papaveraceae): A Chemical and Biological Review

作者:Yu Xuelong; Gao Xiaoli; Zhu Zhixiang; Cao Yuan; Zhang Qian; Tu Pengfei*; Chai Xingyun
来源:Molecules, 2014, 19(9): 13042-13060.
DOI:10.3390/molecules190913042

摘要

The Bocconieae tribe, consisting of only the genera Macleaya and Bocconia, possesses significant economic and medicinal value and plays an important role in health management for people in developing countries. During the past decades, research on metabolites and relative pharmacology, including the isolation and identification of a variety of molecules, has shed light on the tribe. Among those molecules, isoquinoline alkaloids, and their antimicrobial, antifungal, and anti-inflammatory activities are especially noteworthy. This paper presents a comprehensive compilation of current research progress, with emphasis on the alkaloids and their distribution, phytochemical and pharmacological investigation, toxicity and side effects, related chemotaxonomy and future use prospects, and hopefully provides a valuable reference as an effort to promote further exploration and application of this tribe.