A STUDY ON THE REDUCTION OF 4-CHLORO-1,2-DIHYDROPHOSPHININE OXIDES BY TRANSFER HYDROGENATION

作者：Kovacs Rita; Balogh Gyoergy T; Ludanyi Krisztina; Drahos Laszlo; Keglevich Gyoergy^*

来源：Phosphorus, Sulfur, and Silicon and the Related Elements, 2012, 187(1): 121-127.

DOI：10.1080/10426507.2011.608100

• Transfer hydrogenation
• 1,2-dihydrophosphinine oxide
• 1,2,3,6-tetrahydrophosphinine oxide
• 1,2,3,4,5,6-hexahydrophosphinine oxide
• dechlorination
• intermediate

Under the conditions of transfer hydrogenation by ammonium formate, the title compounds (6) were converted to a mixture of the corresponding 1,2,3,6-tetrahyidrophosphinine oxide (7), its dechlorinated derivative (8) and the respective 1,2,3,4,5,6-hexahydrophosphinine oxide (9). In the phenyl-substituted instance, the ratios of the components depended on the mode of heating (traditional heating or microwave irradiation), temperature, and the solvent (toluene or [bmim][BF4]) used. In the ethoxy-substituted series, the dechlorinated 1,2-dihydrophosphinine oxide (10b) was detected as an intermediate.