A tryptophan-analog host whose interactions with ammonium ions in water are dominated by the hydrophobic effect

作者：Whiting Amanda L; Neufeld Nicole M; Hof Fraser^*

来源：Tetrahedron Letters, 2009, 50(50): 7035-7037.

DOI：10.1016/j.tetlet.2009.09.161

• Cation-pi interaction
• Hydrophobic effect
• Quaternary ammonium ions
• NMR titration
• Aromatic cage

The binding of quaternary ammonium guests to a flexible, indole-based host has been studied in both aqueous and organic solvents. Binding was shown to depend strongly on the hydrophobic effect and less on the cation-pi interaction.

• 出版日期2009-12-16