Ni-Catalyzed Stereoselective Arylation of Inert C-O bonds at Low Temperatures

作者：Cornella Josep; Martin Ruben^*

来源：Organic Letters, 2013, 15(24): 6298-6301.

DOI：10.1021/ol4031815

A Ni-catalyzed arylation of inert C-O bonds that operates at temperatures as low as -40 degrees C is described. Unlike other methods for C-O bond cleavage utilizing organometallic species, this protocol operates at low temperatures, thus allowing the presence of sensitive functional groups with exquisite site-selectivity and stereoselectivity.

• 出版日期2013-12-20