Asymmetric sp(3) C-H functionalization via a chiral Bronsted acid-catalyzed redox reaction for the synthesis of cyclic aminals

作者：He Yu Ping; Du Yu Liu; Luo Shi Wei; Gong Liu Zhu^*

来源：Tetrahedron Letters, 2011, 52(52): 7064-7066.

DOI：10.1016/j.tetlet.2011.10.062

• Asymmetric catalysis
• 1,5-Hydride shift
• Bronsted acid
• Cyclic aminals

An organocatalytic asymmetric tandem 1,5-hydride transfer/ring closing reaction of o-aminobenzoketones with anilines to give cyclic aminals in fairly good diastereo- and enantioselectivities.

• 出版日期2011-12-28
• 单位中国科学技术大学