摘要
Chemical investigation of the chloroform extract of the Egyptian Red Sea soft coral, Heteroxenia ghardaqensis (Family Xeniidae), led to the isolation of three gorgostane derivatives, namely gorgosten-5(E)-3-ol (1), gorgostan-3,5,6, 11-tetraol (sarcoaldosterol A) (2) and gorgostan-3,5,6-triol-11-acetate (3). To our knowledge, sterol 3 is reported in this article for the first time. The structure elucidation of these compounds was deduced by 1-D and 2-D NMR as well as ESIMS. Sterol 1 showed moderate activity as growth inhibitor of human colon tumour cell lines.
- 出版日期2013-7-1