Multiple extraspinal recurrences of ependymoma 13 years after spinal cordectomy: case report

作者:Whitaker Lea Wittstatt Alexandra*; Graham Robert Scott; Muizelaar Jan Paul; Richard Hope T
来源:Journal of Neurosurgery-Spine, 2018, 29(1): 92-96.
DOI:10.3171/2017.12.SPINE17848

摘要

Ependymomas of the spinal cord remain confined to the CNS and vary in presentation, depending on WHO grade. Higher-grade lesions usually cannot be surgically removed due to their infiltrative growth pattern. Spinal cordectomy has been proposed as a rescue treatment to improve survival in patients with high-grade as well as recurrent lesions. This report details an instructive and unique case of long-term follow-up of a patient who underwent cordectomy from T-4 through S-5 for what was initially diagnosed as a high-grade glial neoplasm of the spinal cord in 1993. The patient lived symptom free for 13 years after spinal cord resection and then presented with numerous bilateral extraspinal (intraab-dominal and intrathoracic) tumors, which eventually led to her death 15 years after the cordectomy. In this case, spinal cordectomy was effective in preventing the ascending spread of the neoplasm, but ultimately not effective in preventing recurrence in the plicated distal dural sac.

  • 出版日期2018-7

全文