DDQ-Promoted C-S Bond Formation: Synthesis of 2-Aminobenzothiazole Derivatives under Transition-Metal-, Ligand-, and Base-Free Conditions

作者：Wang Rui^*; Yang Wen juan; Yue Liang; Pan Wei; Zeng Hong yao

来源：Synlett, 2012, 23(11): 1643-1648.

DOI：10.1055/s-0031-1291159

• 2-aminobenzothiazoles
• transition-metal-free
• ligand-free
• DDQ
• S-arylation

A transition-metal-free method for the intramolecular S-arylation of o-halobenzothiaoureas via DDQ-mediated leading to the 2-aminobenzothiazole derivatives is reported. The reactions are performed at room temperature under ligand-and base-free conditions with good to excellent yields.

• 出版日期2012-7
• 单位重庆理工大学; 乐山师范学院