A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic

作者:Baumann Marcus; Baxendale Ian R; Deplante Fabien
来源:Beilstein Journal of Organic Chemistry, 2017, 13: 2549-2560.
DOI:10.3762/bjoc.13.251

摘要

<jats:p>An assembled suite of flow-based transformations have been used to rapidly scale-up the production of a novel auxin mimic-based herbicide which was required for preliminary field trials. The overall synthetic approach and optimisation studies are described along with a full description of the final reactor configurations employed for the synthesis as well as the downstream processing of the reaction streams.</jats:p>

  • 出版日期2017-11-29