A gold-catalysed imine-propargylamine cascade sequence: synthesis of 3-substituted-2,5-dimethylpyrazines and the reaction mechanism

作者：Alcaide Benito^*; Almendros Pedro; Alonso Jose M; Fernandez Israel; Gomez Campillos Gonzalo; Rosario Torres M

来源：Chemical communications, 2014, 50(35): 4567-4570.

DOI：10.1039/c4cc01485e

The gold-catalysed coupling reaction between propargylamine-derived imines and propargylamine exclusively afforded pyrazines. Besides, in order to understand the mechanism of this sequence, deuterium labeling and computational studies have been performed.

• 出版日期2014