Amine Functionalized Graphene Electrochemical Biosensor for Simultaneous Determination of Small Biomolecules

作者：Jing, Aihua; Zhang, Chunxin; Zhu, Yunchen; Tian, Zhengshan; Feng, Wenpo; Liang, Gaofeng^*

来源：Nanoscience and Nanotechnology Letters, 2018, 10(7): 950-955.

DOI：10.1166/nnl.2018.2699

• Graphene
• Electrochemical
• Ascorbic Acid
• Dopamine
• Uric Acid

Electrochemical biosensor of amine-functionalized graphene (AG) for simultaneous detection of ascorbic acid (AA), dopamine (DA) and uric acid (UA) in human serum is reported in this study. The amine-functionalized graphene was obtained by ammoniated reaction on graphene oxide and was fabricated on glass carbon electrode as a sensing platform. High sensitivity and selectivity were obtained, and simultaneous electrochemical determination of AA, DA and UA displays linear response ranges of 1.5 x 10(-5)similar to 1.0 x 10(-3) M, 1.0 x 10(-7)similar to 1.0 x 10(-4) M and 1.2 x 10(-5)similar to 5.0 x 10(-2) M, respectively. The anode peak values for AA and DA, DA and UA, UA and AA, were 0.21 V, 0.18 V and 0.35 V, respectively. This finding demonstrates that the AG/GCE electrode can be used as a biosensor for detecting three analytes in human serum.

• 出版日期2018-7
• 单位平顶山学院; 河南大学